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Site-Selective and Stereoselective trans-Hydroboration of 1,3-Enynes Catalyzed by 1,4-Azaborine-Based Phosphine-Pd Complex

Senmiao Xu, Yuanzhe Zhang, Bo Li and Shih-Yuan Liu*

*Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467-3860, United States, Email:

S. Xu, Y. Zhang, B. Li, S.-Y. Liu, J. Am. Chem. Soc., 2016, 138, 14566-14569.

DOI: 10.1021/jacs.6b09759 (free Supporting Information)


Monobenzofused 1,4-azaborine phosphine ligands uniquely support Pd-catalyzed trans-selective hydroboration of terminal and internal 1,3-enynes to furnish the corresponding dienylboronates in high efficiency and diastereoselectivity.

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ID: J48-Y2016