An Effective Pd-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid
Wenlong Ren, Wenju Chang, Jie Dai, Yuan Shi, Jingfu Li and Yian Shi*
*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States, Email: Yian.Shicolostate.edu
W. Ren, W. Chang, J. Dai, Y. Shi, J. Li, Y. Shi, J. Am. Chem. Soc., 2016, 138, 14864-14867.
DOI: 10.1021/jacs.6b10297 (free Supporting Information)
An effective and operationally simple palladium-catalyzed regioselective hydroformylation of olefins with formic acid provides linear aldehydes in good yield with excellent regioselectivity. 1,3-Bis(diphenylphosphino)propane (dppp) as the ligand plays a crucial role in directing the reaction pathway. The process requires no syngas.
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