An Effective Pd-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid
Wenlong Ren, Wenju Chang, Jie Dai, Yuan Shi, Jingfu Li and Yian Shi*
*Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States, Email: Yian.Shicolostate.edu
W. Ren, W. Chang, J. Dai, Y. Shi, J. Li, Y. Shi, J. Am. Chem. Soc., 2016, 138, 14864-14867.
An effective and operationally simple palladium-catalyzed regioselective hydroformylation of olefins with formic acid provides linear aldehydes in good yield with excellent regioselectivity. 1,3-Bis(diphenylphosphino)propane (dppp) as the ligand plays a crucial role in directing the reaction pathway. The process requires no syngas.
see article for more examples
Pd-Catalyzed Highly Chemo- and Regioselective Hydrocarboxylation of Terminal Alkyl Olefins with Formic Acid
W. Ren, J. Chu, F. Sun, Y. Shi, Org. Lett., 2019, 21, 5967-5970.
A Ligand-Directed Catalytic Regioselective Hydrocarboxylation of Aryl Olefins with Pd and Formic Acid
W. Liu, W. Ren, J. Li, Y. Shi, W. Chang, Y. Shi, Org. Lett., 2017, 19, 1748-1751.
Palladium-Catalyzed Highly Regio- and Enantioselective Hydroesterification of Aryl Olefins with Phenyl Formate
J. Li, W. Chang, W. Ren, J. Dai, Y. Shi, Org. Lett., 2016, 18, 5456-5459.
Facile Palladium-Catalyzed Hydrocarboxylation of Olefins without External CO Gas
Y. Wang, W. Ren, J. Li, H. Wang, Y. Shi, Org. Lett., 2014, 16, 5960-5963.