Pyridine-Catalyzed Radical Borylation of Aryl Halides
Li Zhang and Lei Jiao*
*Center of Basic Molecular Science (CBMS), Department of Chemistry, Tsinghua University, Beijing 10084, China, Email: Leijiaomail.tsinghua.edu.cn
L. Zhang, L. Jiao, J. Am. Chem. Soc., 2017, 139, 607-610.
DOI: 10.1021/jacs.6b11813 (free Supporting Information)
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A selective cross-coupling of an aryl radical and a pyridine-stabilized boryl radical enables a transition-metal-free borylation reaction of haloarenes under mild conditions. This pyridine-catalyzed borylation features a broad substrate scope, operational simplicity, and gram-scale synthetic ability.
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L. Zhang, L. Jiao, J. Am. Chem. Soc., 2019, 141, 9124-9128.