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Transfer Hydro-dehalogenation of Organic Halides Catalyzed by Ruthenium(II) Complex

Tingjie You, Zhenrong Wang, Jiajia Chen and Yuanzhi Xia*

*College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China, Email:

T. You, Z. Wang, J. Chen, Y. Xia, J. Org. Chem., 2017, 82, 1340-1346.

DOI: 10.1021/acs.joc.6b02222

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A simple and efficient Ru(II)-catalyzed transfer hydro-dehalogenation using 2-propanol as the hydride source is applicable for various aromatic halides and α-haloesters and amides. The potential synthetic application of this method was demonstrated by efficient gram-scale transformation with catalyst loading as low as 0.5 mol %.

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Key Words

dehalogenation, 2-propanol

ID: J42-Y2017