Synthesis of Sulfones and Sulfonamides via Sulfinate Anions: Revisiting the Utility of Thiosulfonates
Pranab K. Shyam and Hye-Young Jang*
*Department of Energy Systems Research, Ajou University,
Suwon 16499, Korea,
Email: hyjang2
ajou.ac.kr
P. K. Shyam, H.-Y. Jang, J. Org. Chem., 2017, 82, 1761-1767.
DOI: 10.1021/acs.joc.6b03016
see article for more reactions
Abstract
Thiosulfonates synthesized by copper-catalyzed aerobic dimerization serve as substrate for simple and high-yielding strategies for the production of a variety of sulfones and sulfonamides. Thiosulfinates are stable, nontoxic alternatives to metal sulfinate salts derived from toxic SO2.
see article for more examples
Key Words
benzyl sulfones, sulfonamides, NBS
ID: J42-Y2017
