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Csp-Csp3 Bond Formation via Iron(III)-Promoted Hydroalkynylation of Unactivated Alkenes

Yangyong Shen, Bo Huang, Jing Zheng, Chen Lin, Yu Liu and Sunliang Cui*

*Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, Zhejiang, China, Email:

Y. Shen, B. Huang, J. Zheng, C. Lin, Y. Liu, S. Cui, Org. Lett., 2017, 19, 1744-1747.

DOI: 10.1021/acs.orglett.7b00499

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An iron(III)-promoted hydroalkynylation of unactivated mono-, di-, and trisubstituted alkenes provides structural diversified alkynes via Csp-Csp3 bond formation.

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Key Words

alkynylation, phenylsilane

ID: J54-Y2017