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Palladium-Catalyzed Electrochemical Allylic Alkylation between Alkyl and Allylic Halides in Aqueous Solution

Yin-Long Lai and Jing-Mei Huang*

*Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong 510640, China, Email:

Y.-L. Lai, J.-M. Huang, Org. Lett., 2017, 19, 2022-2025.

DOI: 10.1021/acs.orglett.7b00473

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Electrochemistry enables smooth Zn-mediated allylic alkylations in aqueous media under air in the presence of a Pd catalyst between a full range of alkyl halides (primary, secondary, and tertiary) and substituted allylic halides.

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Key Words

allylation, benzylation, electrochemistry, Zn

ID: J54-Y2017