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Copper-Catalyzed Regioselective Synthesis of Multisubstituted Furans by Coupling between Ketones and Aromatic Olefins

Amrita Dey, Md Ashif Ali, Sourav Jana and Alakananda Hajra*

*Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India, Email: alakananda.hajravisva-bharati.ac.in

A. Dey, M. A. Ali, S. Jana, A. Hajra, J. Org. Chem., 2017, 82, 4812-4818.

DOI: 10.1021/acs.joc.7b00476 (free Supporting Information)


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Abstract

A regioselective, Cu(II)-catalyzed intermolecular annulation of aryl ketones with a wide range of aromatic olefins under ambient air provides multisubstituted furan derivatives in good yields. This protocol is applicable to both cyclic and acyclic aryl ketones.

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Key Words

furans, air


ID: J42-Y2017