Organic Chemistry Portal



Copper-Catalyzed Regioselective Synthesis of Multisubstituted Furans by Coupling between Ketones and Aromatic Olefins

Amrita Dey, Md Ashif Ali, Sourav Jana and Alakananda Hajra*

*Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India, Email:

A. Dey, M. A. Ali, S. Jana, A. Hajra, J. Org. Chem., 2017, 82, 4812-4818.

DOI: 10.1021/acs.joc.7b00476

see article for more reactions


A regioselective, Cu(II)-catalyzed intermolecular annulation of aryl ketones with a wide range of aromatic olefins under ambient air provides multisubstituted furan derivatives in good yields. This protocol is applicable to both cyclic and acyclic aryl ketones.

see article for more examples

Key Words

furans, air

ID: J42-Y2017