Iodine-Catalyzed Facile Approach to Sulfones Employing TosMIC as a Sulfonylating Agent
Lingaswamy Kadari, Radha Krishna Palakodety* and Lakshmi Prapurna Yallapragada*
*D-207, Discovery Laboratory, Organic and Biomolecular
Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad
500007, India,
Email: prkgenius
iict.res.in, ylprapurna.iictgov.in
L. Kadari, R. K. Palakodety, L. P. Yallapragada, Org. Lett., 2017, 19, 2580-2583.
DOI: 10.1021/acs.orglett.7b00896
see article for more reactions
Abstract
An iodine-catalyzed functionalization of various olefins and alkynes and direct decarboxylative functionalization of cinnamic and propiolic acids with TosMIC provides highy valuable vinyl, allyl, and β-iodo vinylsulfones. This simple, efficient, and environmentally benign approach is attractive to both synthetic and medicinal chemistry.
see article for more examples
Key Words
vinyl sulfones, allyl sulfones
ID: J54-Y2017
