tert-Butyl Nitrite-Mediated Synthesis of N-Nitrosoamides, Carboxylic Acids, Benzocoumarins, and Isocoumarins from Amides
Subhash L. Yedage and Bhalchandra M. Bhanage*
*Department of Chemistry, Institute of Chemical Technology, Mumbai 400019, India, Email: bm.bhanageictmumbai.edu.in
S. L. Yedage, B. M. Bhanage, J. Org. Chem., 2017, 82, 5769-5781.
DOI: 10.1021/acs.joc.7b00570 (free Supporting Information)
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tert-Butyl nitrite (TBN) is a multitask reagent for the controlled synthesis of N-nitrosoamides from N-alkyl amides, hydrolysis of N-methoxyamides to carboxylic acids, metal-free benzocoumarin synthesis from ortho-aryl-N-methoxyamides, and Ru-catalyzed isocoumarin synthesis.
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