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Highly Enantioselective Cobalt-Catalyzed Hydrosilylation of Alkenes

Biao Cheng, Peng Lu, Heyi Zhang, Xinpeng Cheng and Zhan Lu*

*Department of Chemistry, Zhejiang University, Hangzhou 310058, China, Email: luzhanzju.edu.cn

B. Cheng, P. Lu, H. Zhang, X. Cheng, Z. Lu, J. Am. Chem. Soc., 2017, 139, 9439-9442.

DOI: 10.1021/jacs.7b04137



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Abstract

A cobalt-catalyzed enantioselective hydrosilylation of terminal alkenes enables an efficient synthesis of valuable chiral dihydrosilanes. This protocol is operationally simple and atom-economic using relatively simple and readily available starting materials.

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Key Words

benzylsilanes, alkylsilanes


ID: J48-Y2017