Ligand-Accelerated Gold-Catalyzed Addition of in Situ Generated Hydrazoic Acid to Alkynes under Neat Conditions
Xiaoqing Li, Shengrong Liao, Zhixun Wang and Liming Zhang*
*Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, United States, Email: zhangchem.ucsb.edu
X. Li, S. Liao, Z. Wang, L. Zhang, Org. Lett., 2017, 19, 3687-3690.
see article for more reactions
Low loadings of a gold catalyst derived from a functionalized biaryl-2-ylphosphine ligand (WangPhos) enable a direct addition of in situ generated hydrazoic acid to terminal as well as internal alkynes.
see article for more examples