Iridium(III)-Catalyzed One-Pot Access to 1,2-Disubstituted Benzimidazoles Starting from Imidamides and Sulfonyl Azides
Linhua Xu, Lianhui Wang, Yadong Feng, Yudong Li, Lei Yang and Xiuling Cui*
*Engineering Research Center of Molecular Medicine of
Ministry of Education, School of Biomedical Sciences, Huaqiao University, Xiamen
361021, P. R. China, Email: cuixl
hqu.edu.cn
L. Xu, L. Wang, Y. Feng, Y. Li, L. Yang, X. Cui, Org. Lett., 2017, 19, 4343-4346.
DOI: 10.1021/acs.orglett.7b02028
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Abstract
A mild, Ir-catalyzed annulation of imidamides with sulfonyl azides provides 1,2-disubstituted benzimidazoles in very good yield. This method offers high regioselectivity, efficiency, and good tolerance of functional groups.
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Key Words
ID: J54-Y2017
