A C-H Activation-Based Strategy for N-Amino Azaheterocycle Synthesis
Pengfei Shi, Lili Wang, Shan Guo, Kehao Chen, Jie Wang and Jin Zhu*
*School of Chemistry and Chemical Engineering, Collaborative
Innovation Center of Chemistry for Life Sciences, Nanjing University, Nanjing
210023, China, Email: jinz
nju.edu.cn
P. Shi, L. Wang, S. Guo, K. Chen, J. Wang, J. Zhu, Org. Lett., 2017, 19, 4359-4362.
DOI: 10.1021/acs.orglett.7b02066
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Abstract
Rh(III)-catalyzed coupling of N-Boc hydrazones/N-Boc hydrazines with diazodiesters/diazoketoesters provides convenient access to synthetically and medicinally important N-amino isoquinolin-3-ones and N-amino indoles via a C-H activation-based strategy.
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Key Words
ID: J54-Y2017
