Synthesis of Cyclic Imides by Acceptorless Dehydrogenative Coupling of Diols and Amines Catalyzed by a Manganese Pincer Complex
Noel Angel Espinosa-Jalapa, Amit Kumar, Gregory Leitus, Yael Diskin-Posner and David Milstein*
*Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot, 76100, Israel, Email: david.milsteinweizmann.ac.il
N. Angel Espinosa-Jalapa, A. Kumar, G. Leitus, Y. Diskin-Posner, D. Milstein, J. Am. Chem. Soc., 2017, 139, 11722-11725.
DOI: 10.1021/jacs.7b08341 (free Supporting Information)
A manganese pincer complex catalyzes a dehydrogenative coupling of diols and amines to form cyclic imides. The reaction forms hydrogen gas as the sole byproduct, making the overall process atom economical and environmentally benign.
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proposed catalytic cycle