Palladium-Catalyzed Sequential Nucleophilic Addition/Oxidative Annulation of Bromoalkynes with Benzoic Acids To Construct Functionalized Isocoumarins
Guangbin Jiang, JianXiao Li, Chuanle Zhu, Wanqing Wu* and Huanfeng Jiang*
*School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P. R. China, Email: cewuwqscut.edu.cn, jianghfscut.edu.cn
G. Jiang, J. Li, C. Zhu, W. Wu, H. Jiang, Org. Lett., 2017, 19, 4440-4443.
DOI: 10.1021/acs.orglett.7b01919 (free Supporting Information)
An efficient and robust palladium-catalyzed nucleophilic addition/oxidative annulation of bromoalkynes with benzoic acids provides 3-substituted isocoumarins.
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