Organic Chemistry Portal

Abstracts

Search:

Synthesis of 3-Aryl-2-pyrones by Palladium-Catalyzed Cross-Coupling of Aryl Iodides with Cyclic Vinyldiazo Ester

Jun Huang, Linyong Li, Haoguo Chen, Tiebo Xiao, Yuwei He and Lei Zhou*

*School of Chemistry, Sun Yat-Sen University, 135 Xingang West Road, Guangzhou 510275, China, Email: zhoul39mail.sysu.edu.cn

J. Huang, L. Li, H. Chen, T. Xiao, Y. He, L. Zhou, J. Org. Chem., 2017, 82, 9204-9209.

DOI: 10.1021/acs.joc.7b01470 (free Supporting Information)



see article for more reactions

Abstract

A palladium-catalyzed cross-coupling reaction of cyclic vinyldiazo ester with aryl iodides provides various 3-aryl-2-pyrones in good yields with high functional group tolerance. The resulting 3-aryl-2-pyrones can be used as diene components in Diels-Alder reactions.

see article for more examples

proposed mechanism



Key Words

2-pyrones


ID: J42-Y2017