Organic Chemistry Portal

Abstracts

Search:

Potassium tert-Butoxide Mediated Arylation of 2-Substituted Malononitriles Using Diaryliodonium Salts

Jianwei Han*, Xiaofei Qian, Bowen Xu, Limin Wang*

*School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. of China, Email: jianweihanecust.edu.cn, wangliminecust.edu.cn

J. Han, X. Qian, B. Xu, L. Wang, Synlett, 2017, 28, 2139-2142.

DOI: 10.1055/s-0036-1589061 (free Supporting Information)



see article for more reactions

Abstract

Potassium tert-butoxide promotes a direct arylation of 2-substituted malononitriles using diaryliodonium salts without transition-metal catalysts. The desired 2-substituted α-arylmalononitriles derivatives were synthesized in very good yields.

see article for more examples



Key Words

arylation, diaryliodonium salts, metal-free, arylmalononitriles


ID: J60-Y2017