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Fine-Bubble-Based Strategy for the Palladium-Catalyzed Hydrogenation of Nitro Groups: Measurement of Ultrafine Bubbles in Organic Solvents

Nobuyuki Mase*, Yuki Nishina, Shogo Isomura, Kohei Sato, Tetsuo Narumi, Naoharu Watanabe

*Graduate School of Science and Technology, Shizuoka University, Shizuoka, 432-8561, Japan, Email:

N. Mase, Y. Nishina, S. Isomura, K. Sato, T. Narumi, N. Watanabe, Synlett, 2017, 28, 2184-2188.

DOI: 10.1055/s-0036-1588869 (free Supporting Information)

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The use of H2-fine bubbles as a new reaction medium enables an autoclave-free gas-liquid-solid multiphase hydrogenation of nitro groups on a multigram scale.

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Key Words

microbubbles, ultrafine bubbles, hydrogenation of nitro compounds, hydrogen, heterogeneous catalysis, green chemistry

ID: J60-Y2017