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Direct Palladium-Catalyzed Carbonylative Transformation of Allylic Alcohols and Related Derivatives

Fu-Peng Wu, Jin-Bao Peng*, Lu-Yang Fu, Xinxin Qi and Xiao-Feng Wu*

*Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, People's Republic of China; Universität Rostock, Albert-Einstein-Straße 29a, Rostock 18059, Germany, Email:,

F.-P. Wu, J.-B. Peng, L.-Y. Fu, X. Qi, X.-F. Wu, Org. Lett., 2017, 19, 5474-5477.

DOI: 10.1021/acs.orglett.7b02801

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A direct, palladium-catalyzed, carbonylative transformation of allylic alcohols in the presence of formic acid as the CO source provides β,γ-unsaturated carboxylic acids with excellent linear and (E)-selectivity under mild conditions.

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proposed mechanism

Key Words

carboxylic acids, allylation

ID: J54-Y2017