Phosphinoyl Radical Initiated Vicinal Cyanophosphinoylation of Alkenes
Pei-Zhi Zhang, Ling Zhang, Jian-An Li, Adedamola Shoberu, Jian-Ping Zou* and Wei Zhang*
*Soochow University, Jiangsu 215123, China; University of Massachusetts, Boston, Massachusetts 02125, United States, Email: jpzousuda.edu.cn, wei2.zhangumb.edu
P.-Z. Zhang, L. Zhang, J.-A. Li, A. Shoberu, J.-P. Zou, W. Zhang, Org. Lett., 2017, 19, 5537-5540.
DOI: 10.1021/acs.orglett.7b02621 (free Supporting Information)
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Mn(OAc)3-mediated phosphinoyl radical addition followed by CuCN-catalyzed cyanation enables a double-functionalization reaction of alkenes under mild conditions to afford vicinal cyanophosphinoylation products.
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