Enantioselective Rhodium-Catalyzed Alkenylation of Aliphatic Imines
Xue-Wei Qian, Ze-Jian Xue, Qian Zhao, Zhe Cui, Ya-Jing Chen, Chen-Guo Feng* and Guo-Qiang Lin*
*Key Laboratory of Synthetic Chemistry of Natural Substances,
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai
200032, P.R. China,
Email: fengcg
sioc.ac.cn, lingqsioc.ac.cn
X.-W. Qian, Z.-J. Xue, Q. Zhao, Z. Cui, Y.-J. Chen, C.-G. Feng, G.-Q. Lin, Org. Lett., 2017, 19, 5601-5604.
DOI: 10.1021/acs.orglett.7b02737
see article for more reactions
Abstract
An efficient, enantioselective rhodium-catalyzed addition of potassium alkenyltrifluoroborates to N-nosyl aliphatic imines offers good reaction yields and excellent enantioselectivities for various aliphatic imines and nucleophilic alkenyltrifluoroborates.
see article for more examples
Enantioselective Alkenylation of Aldimines Catalyzed by a Rhodium-Diene Complex
Z. Cui, Y.-J. Chen, W.-Y. Gao, C.-G. Feng, G.-Q. Lin, Org. Lett., 2014, 16, 1016-1019.
Key Words
ID: J54-Y2017
