Oxidative Synthesis of Benzimidazoles, Quinoxalines, and Benzoxazoles from Primary Amines by ortho-Quinone Catalysis
Ruipu Zhang, Yan Qin, Long Zhang and Sanzhong Luo*
*Key Laboratory for Molecular Recognition and Function,
Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China,
Email: luosz
iccas.ac.cn
R. Zhang, Y. Qin, L. Zhang, S. Luo, Org. Lett., 2017, 19, 5629-5632.
DOI: 10.1021/acs.orglett.7b02786
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Abstract
Bioinspired ortho-quinone catalysts have been applied to oxidative synthesis of benzimidazoles, quinoxalines and benzoxazoles from primary amines in high yields under mild conditions with oxygen as the terminal oxidant.
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Key Words
Benzimidazoles, Quinoxalines, Oxygen, Organocatalysis
ID: J54-Y2017
