Oxidative Synthesis of Benzimidazoles, Quinoxalines, and Benzoxazoles from Primary Amines by ortho-Quinone Catalysis
Ruipu Zhang, Yan Qin, Long Zhang and Sanzhong Luo*
*Key Laboratory for Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China, Email: luosziccas.ac.cn
R. Zhang, Y. Qin, L. Zhang, S. Luo, Org. Lett., 2017, 19, 5629-5632.
DOI: 10.1021/acs.orglett.7b02786 (free Supporting Information)
see article for more reactions
Bioinspired ortho-quinone catalysts have been applied to oxidative synthesis of benzimidazoles, quinoxalines and benzoxazoles from primary amines in high yields under mild conditions with oxygen as the terminal oxidant.
see article for more examples