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Selective Oxidation of Secondary Amines to N,N-Disubstituted Hydroxylamines by Choline Peroxydisulfate

Alireza Banan, Hassan Valizadeh, Akbar Heydari*, Abolghasem Moghimi

*Department of Chemistry, Faculty of Sciences, Azerbajan Shahid Madani University, 53714-161 Tabriz, Iran, Email:

A. Banan, H. Valizadeh, A. Heydari, A. Moghimi, Synlett, 2017, 28, 2315-2319.

DOI: 10.1055/s-0036-1589089


Choline peroxydisulfate - an oxidizing task-specific ionic liquid - enables the preparation of N,N-disubstituted hydroxylamines from secondary amines. This method offers operational simplicity, high selectivity, and green reaction conditions.

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preparation of choline peroxydisulfate

Key Words

hydroxylamines, ionic liquids, choline peroxydisulfate, oxidation, amines, green chemistry

ID: J60-Y2017