Iron-Catalyzed Carbene Insertion Reactions of α-Diazoesters into Si-H Bonds
Hoda Keipour and Thierry Ollevier*
*Département de Chimie, Université Laval, 1045 avenue de la Médecine, Québec, QC G1V 0A6, Canada, Email: thierry.ollevierchm.ulaval.ca
H. Keipour, T. Ollevier, Org. Lett., 2017, 19, 5736-5739.
DOI: 10.1021/acs.orglett.7b02488
see article for more reactions
Abstract
An efficient carbene insertion reaction of α-diazoesters into Si-H bond provides a wide range of α-silylesters in high yields using a simple iron(II) salt as catalyst.
see article for more examples
proposed mechanism
H. Keipour, A. Jalba, L. Delage-Laurin, T. Ollevier, J. Org. Chem., 2017, 82, 3000-3010.
Key Words
ID: J54-Y2017