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Iron-Catalyzed Carbene Insertion Reactions of α-Diazoesters into Si-H Bonds

Hoda Keipour and Thierry Ollevier*

*Département de Chimie, Université Laval, 1045 avenue de la Médecine, Québec, QC G1V 0A6, Canada, Email: thierry.ollevierchm.ulaval.ca

H. Keipour, T. Ollevier, Org. Lett., 2017, 19, 5736-5739.

DOI: 10.1021/acs.orglett.7b02488 (free Supporting Information)


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Abstract

An efficient carbene insertion reaction of α-diazoesters into Si-H bond provides a wide range of α-silylesters in high yields using a simple iron(II) salt as catalyst.

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proposed mechanism



Copper-Catalyzed Carbenoid Insertion Reactions of α-Diazoesters and α-Diazoketones into Si-H and S-H Bonds

H. Keipour, A. Jalba, L. Delage-Laurin, T. Ollevier, J. Org. Chem., 2017, 82, 3000-3010.


Key Words

silanes, benzylsilanes


ID: J54-Y2017