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Synthesis of Azoxybenzenes by Reductive Dimerization of Nitrosobenzene

Yu-Feng Chen, Jing Chen, Li-Jen Lin and Gary Jing Chuang*

*Department of Chemistry, Chung Yuan Christian University, 200 Chung Pei Road, Chung Li district, Taoyuan City, Taiwan 32023, Email:

Y.-F. Chen, J. Chen, L.-J. Lin, G. J. Chuang, J. Org. Chem., 2017, 82, 11620-11630.

DOI: 10.1021/acs.joc.7b01887


Reductive dimerization of nitrosobenzenes enables an effective and simple preparation of substituted azoxybenzenes without additional catalysts/reagents. This procedure can be applied to substrates with a wide range of substitution patterns.

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proposed mechanism

Key Words

azoxy compounds, isopropanol

ID: J42-Y2017