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N-Methylation of Amines with Methanol Catalyzed by a Cp*Ir Complex Bearing a Functional 2,2′-Bibenzimidazole Ligand

Ran Liang, Shun Li, Rongzhou Wang, Lei Lu and Feng Li*

*School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094, P. R. China, Email:

R. Liang, S. Li, R. Wang, L. Lu, F. Li, Org. Lett., 2017, 19, 5790-5793.

DOI: 10.1021/acs.orglett.7b02723

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A Cp*Ir complex bearing a functional 2,2′-bibenzimidazole ligand is a highly effective and general catalyst for the N-methylation of a variety of amines with methanol in the presence of a weak base.

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proposed mechanism

Key Words

arylamines, alkylation

ID: J54-Y2017