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Direct Allylic Amination of Allylic Alcohol Catalyzed by Palladium Complex Bearing Phosphine-Borane Ligand

Goki Hirata, Hideaki Satomura, Hidenobu Kumagae, Aika Shimizu, Gen Onodera* and Masanari Kimura*

*Division of Chemistry and Materials Science, Graduate School of Engineering, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan, Email:,

G. Hirata, H. Satomura, H. Kumagae, A. Shimizu, G. Onodera, M. Kimura, Org. Lett., 2017, 19, 6148-6151.

DOI: 10.1021/acs.orglett.7b03023

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A phosphine-borane compound is an effective ligand for palladium-catalyzed direct allylic amination of allylic alcohols with secondary amines in short reaction times at room temperature.

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proposed mechanism

Key Words


ID: J54-Y2017