Bimetallic Cobalt-Rhodium Nanoparticle-Catalyzed Reductive Amination of Aldehydes with Nitroarenes Under Atmospheric Hydrogen

Isaac Choi, Supill Chun and Young Keun Chung*

*Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, Korea, Email: ykchungsnu.ac.kr

I. Choi, S. Chun, Y. K. Chung, J. Org. Chem., 2017, 82, 12771-12777.

DOI: 10.1021/acs.joc.7b02019

---

see article for more reactions

Abstract

Cobalt-rhodium heterobimetallic nanoparticles catalyze a tandem reductive amination of aldehydes with nitroaromatics without any additives under mild conditions (1 atm H₂ and 25 °C). This procedure can be scaled up to the gram scale, and the catalyst can be reused more than six times without loss of activity.

see article for more examples

---

---

Key Words

reductive amination, hydrogen

---

ID: J42-Y2017