Synthesis of Cyanamides from Cyanogen Bromide under Mild Conditions through N-Cyanation of Allylic Tertiary Amines
Honggang Liang, Lingxiang Bao, Yao Du, Yiying Zhang, Siping Pang, Chenghui Sun*
*School of Materials Science and Engineering, Beijing
Institute of Technology, South Street of No. 5, Zhongguancun, Haidian District,
Beijing, 100081, P. R. of China,
Email: sunch
bit.edu.cn
H. Liang, L. Bao, Y. Du, Y. Zhang, S. Pang, C. Sun, Synlett, 2017, 28, 2675-2679.
DOI: 10.1055/s-0036-1588533
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Abstract
Cyanamides were selectively formed in good yields through a one-step nucleophilic substitution reaction of allylic tertiary amines with cyanogen bromide under mild reaction conditions via N-deallylation and N-cyanation in one pot.
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Key Words
cyanamides, cyanogen bromide, cyanation, deallylation, allylic amines
ID: J60-Y2017
