Photoredox-Catalyzed Deoxygenative Intramolecular Acylation of Biarylcarboxylic Acids: Access to Fluorenones
Rehanguli Ruzi, Muliang Zhang, Keyume Ablajan* and Chengjian Zhu*
*College of Chemistry and Chemical Engineering, Xinjiang
University, Urumqi 830046; School of Chemistry and Chemical Engineering, Nanjing
University, Nanjing 210023, P. R. China, Email: ablajan209
hotmail.com,
cjzhunju.edu.cn
R. Ruzi, M. Zhang, K. Ablajan, C. Zhu, J. Org. Chem., 2017, 82, 12834-12839.
DOI: 10.1021/acs.joc.7b02197
Abstract
Photoredox catalysis enables an efficient deoxygenative radical cyclization reaction of biarylcarboxylic acids for the synthesis of fluorenones. This photocatalytic intramolecular acyl radical coupling reaction provides valuable fluorenone products with mild conditions, good yields, and good functional-group compatibility.
see article for more examples
proposed mechanism
Key Words
ID: J42-Y2017
