Organic Chemistry Portal

Abstracts

Search:

Iron Catalyzed Hydroboration of Aldehydes and Ketones

Sem Raj Tamang and Michael Findlater*

*Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States, Email: Michael.Findlaterttu.edu

S. R. Tamang, M. Findlater, J. Org. Chem., 2017, 82, 12857-12862.

DOI: 10.1021/acs.joc.7b02020 (free Supporting Information)


Abstract

An operationally convenient hydroboration of aldehydes and ketones employing Fe(acac)3 as precatalyst proceeded efficiently at room temperature to yield, after work up, 1 and 2 alcohols. A σ-bond metathesis mechanism with an Fe-H intermediate as key reactive species is postulated.

see article for more examples

proposed mechanism



Key Words

reduction of carbonyl compounds, pinacolborane


ID: J42-Y2017