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Molecular Oxygen-Mediated Minisci-Type Radical Alkylation of Heteroarenes with Boronic Acids

Lizhi Zhang and Zhong-Quan Liu*

*State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China, Email: liuzhqlzu.edu.cn

L. Zhang, Z.-Q. Liu, Org. Lett., 2017, 19, 6594-9597.

DOI: 10.1021/acs.orglett.7b03297


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Abstract

Autoxidation of organoboronic acids using 1 atm of O2 enables a simple, clean, and green carbon-carbon bond formation to provide structurally diverse heteroaromatics with medicinally privileged scaffolds.


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Key Words

quinolines, oxygen


ID: J54-Y2017