Copper-Catalyzed C-S Cross-Coupling Reaction: S-Arylation of Arylthioureas
Hui Zhu, Xing Liu, Cai-Zhu Chang, Zhi-Bing Dong*
*School of Chemistry and Environmental Engineering, Wuhan
Institute of Technology, Wuhan 430205, P. R. of China, Email: dzb04982
wit.edu.cn
H. Zhu, X. Liu, C.-Z. Chang, Z.-B. Dong, Synthesis, 2017, 49, 5211-5216.
DOI: 10.1055/s-0036-1590879
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Abstract
A simple and efficient copper-catalyzed S-arylation of arylthioureas provides aryl-isothioureas. This ligand-free method offers good yield, short reaction time, and broad substrate scope.
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Key Words
copper, S-arylation, catalysis, thioureas, isothioureas
ID: J66-Y2017
