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Synthetic Studies Towards the Synthesis of 6-Substituted 3-Fluoro-5,6-dihydropyran-2-ones

Samir K. Mandal*, Apurba Sarkar, Puskin Chakraborty, Ashoke P. Chattopadhyay

*Department of Chemistry, Saldiha College, Saldiha-722173, India, Email:

S. K. Mandal, A. Sarkar, P. Chakraborty, A. P. Chattoapdhyay, Synlett, 2018, 29, 75-78.

DOI: 10.1055/s-0036-1588534 (free Supporting Information)


In a construction of 6-substituted 3-fluoro-5,6-dihydropyran-2-ones under mild conditions, the key step is a Julia-Kocienski olefination.

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Key Words

fluorosulfones, lactones, 5,6-dihydropyran-2-ones, Julia-Kocienski olefination

ID: J60-Y2018