Photoredox-Catalyzed Decarboxylative Alkylation of Silyl Enol Ethers To Synthesize Functionalized Aryl Alkyl Ketones
Weiguang Kong, Changjiang Yu, Hejun An and Qiuling Song*
*Institute of Next Generation Matter Transformation, College
of Chemical Engineering & College of Material Sciences Engineering at Huaqiao
University, 668 Jimei Boulevard, Xiamen, Fujian 361021, P. R. China, Email:
qsong
hqu.edu.cn
W. Kong, C. Yu, H. An, Q. Song, Org. Lett., 2018, 20, 349-352.
DOI: 10.1021/acs.orglett.7b03587
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Abstract
A photoredox-catalyzed decarboxylative alkylation of silyl enol ethers provides diverse functionalized aryl alkyl ketones in good yields using N-(acyloxy)phthalimides as an easy access alkyl radical source under mild and operationally simple conditions.
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proposed mechanism
Key Words
alkylation, photochemistry
ID: J54-Y2018
