Aerobic Oxidation of Alkyl 2-Phenylhydrazinecarboxylates Catalyzed by CuCl and DMAP
Min Hye Kim and Jinho Kim*
*Department of Chemistry, and Research Institute of Natural Sciences, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon 22012, Republic of Korea, Email: jinhoinu.ac.kr
M. H. Kim, J. Kim, J. Org. Chem., 2018, 83, 1673-1679.
DOI: 10.1021/acs.joc.7b03119 (free Supporting Information)
The synthesis of alkyl 2-phenylazocarboxylates largely depended on the stoichiometric use of toxic oxidants. The use of CuCl and DMAP as catalysts enables an environment-friendly aerobic oxidation of alkyl 2-phenylhydrazinecarboxylates to alkyl 2-phenylazocarboxylates under mild conditions.
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