Palladium-Catalyzed Amination of Aryl Sulfoxides
Yuto Yoshida, Shinya Otsuka, Keisuke Nogi and Hideki Yorimitsu*
*Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan, Email: yorikuchem.kyoto-u.ac.jp
Y. Yoshida, S. Otsuka, K. Nogi, H. Yorimitsu, Org. Lett., 2018, 20, 1134-1137.
DOI: 10.1021/acs.orglett.8b00060 (free Supporting Information)
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Palladium/N-heterocyclic carbene (NHC) catalysis achieves an amination of diaryl sulfoxides with anilines and alkylamines. This amination tolerates a wide range of functional groups such as silyl, boryl, methylsulfanyl, and halogen moieties. Regioselective amination of unsymmetrical diaryl sulfoxides was also executed by means of steric bias.
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