Palladium-Catalyzed Amination of Aryl Sulfoxides
Yuto Yoshida, Shinya Otsuka, Keisuke Nogi and Hideki Yorimitsu*
*Department of Chemistry, Graduate School of Science, Kyoto
University, Sakyo-ku, Kyoto 606-8502, Japan, Email: yorikuchem.kyoto-u.ac.jp
Y. Yoshida, S. Otsuka, K. Nogi, H. Yorimitsu, Org. Lett., 2018, 20, 1134-1137.
DOI: 10.1021/acs.orglett.8b00060
see article for more reactions
Abstract
Palladium/N-heterocyclic carbene (NHC) catalysis achieves an amination of diaryl sulfoxides with anilines and alkylamines. This amination tolerates a wide range of functional groups such as silyl, boryl, methylsulfanyl, and halogen moieties. Regioselective amination of unsymmetrical diaryl sulfoxides was also executed by means of steric bias.
see article for more examples
Key Words
ID: J54-Y2018