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Palladium-Catalyzed Amination of Aryl Sulfoxides

Yuto Yoshida, Shinya Otsuka, Keisuke Nogi and Hideki Yorimitsu*

*Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan, Email:

Y. Yoshida, S. Otsuka, K. Nogi, H. Yorimitsu, Org. Lett., 2018, 20, 1134-1137.

DOI: 10.1021/acs.orglett.8b00060 (free Supporting Information)

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Palladium/N-heterocyclic carbene (NHC) catalysis achieves an amination of diaryl sulfoxides with anilines and alkylamines. This amination tolerates a wide range of functional groups such as silyl, boryl, methylsulfanyl, and halogen moieties. Regioselective amination of unsymmetrical diaryl sulfoxides was also executed by means of steric bias.

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Key Words

arylamines, diarylamines

ID: J54-Y2018