Organic Chemistry Portal

Abstracts

Search:

Palladium-Catalyzed Amination of Aryl Sulfoxides

Yuto Yoshida, Shinya Otsuka, Keisuke Nogi and Hideki Yorimitsu*

*Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan, Email: yorikuchem.kyoto-u.ac.jp

Y. Yoshida, S. Otsuka, K. Nogi, H. Yorimitsu, Org. Lett., 2018, 20, 1134-1137.

DOI: 10.1021/acs.orglett.8b00060 (free Supporting Information)


see article for more reactions

Abstract

Palladium/N-heterocyclic carbene (NHC) catalysis achieves an amination of diaryl sulfoxides with anilines and alkylamines. This amination tolerates a wide range of functional groups such as silyl, boryl, methylsulfanyl, and halogen moieties. Regioselective amination of unsymmetrical diaryl sulfoxides was also executed by means of steric bias.

see article for more examples



Key Words

arylamines, diarylamines


ID: J54-Y2018