Enantioselective Copper-Catalyzed Methylboration of Alkenes
Bin Chen, Peng Cao, Yang Liao, Min Wang and Jian Liao*
*Chengdu Institute of Biology, Chinese Academy of Sciences,
Chengdu 610041, People's Republic of China and University of Chinese Academy of
Sciences, Beijing 10049, People's Republic of China, Email: jliao
cib.ac.cn
B. Chen, P. Cao, Y. Liao, M. Wang, J. Liao, Org. Lett., 2018, 20, 1346-1349.
DOI: 10.1021/acs.orglett.7b03860
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Abstract
An enantioselective Cu-catalyzed borylative cross-coupling reaction of alkenes, bis(pinacolato)diboron, and methyl iodide provides the desired methylboration products with excellent diastereoselectivities and enantioselectivities.
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Key Words
boration, benzylation, multicomponent reactions
ID: J54-Y2018
