Synthesis of Di(hetero)arylamines from Nitrosoarenes and Boronic Acids: A General, Mild, and Transition-Metal-Free Coupling
Silvia Roscales and Aurelio G. Csák˙*
*Instituto Pluridisciplinar, Universidad Complutense, Campus
de Excelencia Internacional Moncloa, Paseo de Juan XXIII, 1, 28040 Madrid, Spain, Email:
csaky
ucm.es
S. Roscales, A. G. Csák˙, Org. Lett., 2018, 20, 1667-1671.
DOI: 10.1021/acs.orglett.8b00473
Abstract
An experimentally simple, fast, mild, and scalable transition-metal-free cross-coupling between boronic acids and nitrosoarenes enables the synthesis of di(hetero)arylamines. The procedure tolerates a wide range of functional groups, including carbonyls, nitro, halogens, free OH and NH groups, and also permits the synthesis of sterically hindered compounds.
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Key Words
diarylamines, triethylphosphite
ID: J54-Y2018
