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Photochemical Nickel-Catalyzed Reductive Migratory Cross-Coupling of Alkyl Bromides with Aryl Bromides

Long Peng, Zheqi Li and Guoyin Yin*

*The Institute for Advanced Studies (IAS), Wuhan University, Wuhan, Hubei 430072, P. R. China, Email:

L. Peng, Z. Li, G. Yin, Org. Lett., 2018, 20, 1880-1883.

DOI: 10.1021/acs.orglett.8b00413

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A visible-light-driven nickel and iridium dual catalysis enables the migratory benzylic arylation of nonactivated alkyl bromides with aryl bromides to provide 1,1-diarylalkanes in the presence of diisopropylamine as the terminal reductant. This method tolerates a wide range of functional groups.

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Key Words

diarylmethanes, photochemistry

ID: J54-Y2018