Iron-Catalyzed Highly Enantioselective Hydrosilylation of Unactivated Terminal Alkenes
Biao Cheng, Wenbo Liu and Zhan Lu*
*Department of Chemistry, Zhejiang University, Hangzhou
310058, China, Email: luzhan
zju.edu.cn
B. Cheng, W. Liu, Z. Lu, J. Am. Chem. Soc., 2018, 140, 5014-5017.
DOI: 10.1021/jacs.8b01638
see article for more reactions
Abstract
An iron-catalyzed highly Markovnikov-type selective and enantioselective hydrosilylation of terminal aliphatic alkenes with good functional group tolerance provides valuable chiral organosilanes with high ees. Chiral aliphatic alkan-2-ols could be efficiently synthesized via further derivatization of chiral organosilanes without any racemization.
see article for more examples
Key Words
ID: J48-Y2018
