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Sulfuric Acid-Promoted Oxidation of Benzylic Alcohols to Aromatic Aldehydes in Dimethyl Sulfoxide: An Efficient Metal-Free Oxidation Approach

Ehsan Sheikhi*, Mehdi Adib*, Morteza Akherati Karajabad, Seyed Jamal Addin Gohari

*School of Chemistry, College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran, Email: ehsan.sheikhigmail.com, madibkhayam.ut.ac.ir

E. Sheikhi, M. Adib, M. A. Karajabad, S. J. A. Gohari, Synlett, 2018, 29, 974-978.

DOI: 10.1055/s-0037-1609149 (free Supporting Information)


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Abstract

The use of DMSO in the presence of H2SO4 enables an efficient metal-free oxidation of benzylic alcohols to aromatic aldehydes in excellent yields. This oxidation proceeds in short reaction time without side products.

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Key Words

benzylic alcohols, aromatic aldehydes, sulfuric acid, dimethyl sulfoxide, oxidation


ID: J60-Y2018