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Nickel-Catalyzed Deoxycyanation of Activated Phenols via Cyanurate Intermediates with Zn(CN)2: A Route to Aryl Nitriles

Majid M. Heravi*, Farhad Panahi* and Nasser Iranpoor

*Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran; Chemistry Department, College of Sciences, Shiraz University, Shiraz 71454, Iran, Email:,

M. M. Heravi, F. Panahi, N. Iranpoor, Org. Lett., 2018, 20, 2753-2756.

DOI: 10.1021/acs.orglett.8b00974

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In an efficient nickel-catalyzed deoxycyanation of activated phenolic compounds, relatively nontoxic Zn(CN)2 can be used as the cyanide source to provide aromatic nitriles in good to excellent yields.

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ID: J54-Y2018