Cu(I)-Catalyzed Aminative Aza-Annulation of Enynyl Azide using N-Fluorobenzenesulfonimide: Synthesis of 5-Aminonicotinates
Chada Raji Reddy*, Santosh Kumar Prajapti and Ravi Ranjan
*Division of Natural Products Chemistry, CSIR-Indian
Institute of Chemical Technology, Hyderabad 500007, India, Email: rajireddy
iict.res.in
C. R. Reddy, S. K. Prajapti, R. Ranjan, Org. Lett., 2018, 20, 3128-3131.
DOI: 10.1021/acs.orglett.8b01228
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Abstract
The use of the commercially available N-fluorobenzenesulfonimide (NFSI) as an amination reagent enables a copper-catalyzed aminative aza-annulation of enynyl azide to provide amino-substituted nicotinate derivatives in a single step in good yield.
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Key Words
ID: J54-Y2018
