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Tf2O-Promoted Intramolecular Schmidt Reaction of the ω-Azido Carboxylic Acids

Xue-Juan Wang, Yan Su, Rui Li and Peiming Gu*

*College of Chemistry & Chemical Engineering, Ningxia Engineering and Research Center for Natural Medicines, Ningxia University, Yinchuan 750021, China, Email: gupmnxu.edu.cn

X.-J. Wang, Y. Su, R. Li, P. Gu, J. Org. Chem., 2018, 83, 5816-5824.

DOI: 10.1021/acs.joc.8b00475 (free Supporting Information)


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Abstract

A Tf2O-promoted intramolecular Schmidt reaction of 2-substituted ω-azido carboxylic acids provides a series of 2-substituted pyrrolidines.

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Key Words

Schmidt reaction, pyrrolidines


ID: J42-Y2018