Cobalt-Catalyzed Regioselective Olefin Isomerization Under Kinetic Control
Xufang Liu, Wei Zhang, Yujie Wang, Ze-Xin Zhang, Lei Jiao* and Qiang Liu*
*Center of Basic Molecular Science (CBMS), Department of
Chemistry, Tsinghua University, Beijing 100084, China, Email: qiang_liu
mail.tsinghua.edu.cn,
leijiaomail.tsinghua.edu.cn
X. Liu, W. Zhang, Y. Wang, Z.-X. Zhang, L. Jiao, Q. Liu, J. Am. Chem. Soc., 2018, 140, 6873-6882.
DOI: 10.1021/jacs.8b01815
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Abstract
A cobalt-catalyzed regioselective olefin isomerization reaction with fine-tunable NNP-pincer ligand structures features high kinetic control of regioselectivity. This mild catalytic system enables the isomerization of 1,1-disubstituted olefins bearing a wide range of functional groups in excellent yields and regioselectivity.
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Key Words
ID: J48-Y2018
