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Cu(I)-Catalyzed Coupling of Bis(trimethylsilyl)diazomethane with Terminal Alkynes: A Synthesis of 1,1-Disilyl Allenes

Shuai Xu, Ri Chen, Zihao Fu, Yunpeng Gao and Jianbo Wang*

*Beijing National Laboratory of Molecular Sciences (BNLMS), College of Chemistry, Peking University, Beijing 100871, China, Email:

S. Xu, R. Chen, Z. Fu, Y. Gao, J. Wang, J. Org. Chem., 2018, 83, 6186-6192.

DOI: 10.1021/acs.joc.8b00651

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An efficient Cu(I)-catalyzed cross-coupling reaction of terminal alkynes and bis(trimethylsilyl)diazomethane provides 1,1-disilyl allenes through metal-carbene migratory insertion. Subsequent transformations of 1,1-disilyl allenes show interesting reactivities.

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ID: J42-Y2018