Adducts of Triallylborane with Ammonia and Aliphatic Amines as Stoichiometric Allylating Agents for Aminoallylation Reaction of Carbonyl Compounds
Nikolai Yu. Kuznetsov*, Rabdan M. Tikhov, Tatiana V. Strelkova and Yuri N. Bubnov
*A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov 28, 119991 Moscow, Russian Federation, Email: nkuznffineos.ac.ru
N. Y. Kuznetsov, R. M. Tikhov, T. V. Strelkova, Y. N. Bubnov, Org. Lett., 2018, 20, 3549-3552.
DOI: 10.1021/acs.orglett.8b01317 (free Supporting Information)
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Triallylborane-amine adducts can be used as stoichiometric allylating agents for efficient aminoallylation reactions of carbonyl compounds in methanol. Moreover, copper catalysis enables a diastereoselective allylation of Ellman's imine.
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