Asymmetric [4 + 2]-Cycloaddition of Copper-Allenylidenes with Hexahydro-1,3,5-triazines: Access to Chiral Tetrahydroquinazolines
Danqing Ji, Cheng Wang and Jiangtao Sun*
*Jiangsu Key Laboratory of Advanced Catalytic Materials &
Technology, School of Petrochemical Engineering, Changzhou University, Changzhou
213164, P. R. China, Email: jtsun
cczu.edu.cn
D. Ji, C. Wang, J. Sun, Org. Lett., 2018, 20, 3710-3713.
DOI: 10.1021/acs.orglett.8b01584
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Abstract
A copper-catalyzed asymmetric formal [4 + 2]-cycloaddition of copper-allenylidenes and hexahydro-1,3,5-triazines provides chiral tetrahydroquinazolines in good yields and with high enantioselectivities for most cases.
see article for more examples
S. Tang, Z. Cheng, P. Zhang, Y. Shao, J. Sun, Org. Lett., 2023, 25, 3639-3643.
Key Words
ID: J54-Y2018
